Spanish
French
Italian
Brazilian Portuguese
Advanced Diploma in Organic Chemistry in Biology and Drug Development
Learn about the application of organic chemistry in biology and drug development with this free online course.
Description
Organic Chemistry in Biology and Drug Development starts with a concise discussion of the different biochemical processes where organic chemistry plays a dominant role. Next, you will study the general concepts of drug design principles. This will be followed by different kinds of drugs and the chemistry of neurotransmitters. After this, you will learn about high throughput screening and combinatorial chemistry.
You will then study the design strategy of antiviral drugs, antimicrobial compounds and the polyketides in connection with the erythromycin polyketides biosynthesis. You will also learn about antiulcer agents which can either be H₂ (hydrogen) antagonists or proton pump inhibitors and antihypertensive drugs. Lastly, you will study the pharmacokinetics and pharmacodynamics of the drug discovery process. This will be followed by the quantitative structure-activity relationship (QSAR), which include principles that can be used to quantify the biological activity of a drug.
This diploma course will be of great interest to professionals working in the pharmaceutical industry such as chemists, biochemists, chemical biologists, druggists and pharmacists. It will equally benefit any learner who would like to have a career in the pharmaceutical sector. So, check out the course and kickstart an exciting career in the field of organic chemistry and drug development.
Start Course NowModules
Introduction to Molecules of Life and Amino Acids
-
Introduction to Molecules of Life and Amino Acids - Learning Outcomes
-
A Brief Introduction to Molecules of Life: Structure of Amino Acids and their Various Charge Form
-
Biological Macromolecules and Small Molecules: Importance and Functions
-
Amino Acids: The Building Block of Proteins
-
Amino Acids: Separation and Detection, Electrophoresis, and Ninhydrin Reaction
-
Introduction to Molecules of Life and Amino Acids - Lesson Summary
Method of Determination of Amino Acid Sequence, and Peptide Synthesis
-
Method of Determination of Amino Acid Sequence, and Peptide Synthesis - Learning Outcomes
-
Method of Determination of Amino Acid Sequence: Primary Structure of Polypeptides/Proteins
-
Selective Peptide Bond Cleavage: Enzymatic and Non-enzymatic Methods
-
Peptide Synthesis: Protecting Groups for Amine and Carboxyl Functionality
-
Peptide Synthesis: Protection, Coupling and Deprotection Methods
-
Recent Development of Coupling Agents: Merrifield’s Method Solid Phase Peptide Synthesis
-
Method of Determination of Amino Acid Sequence, and Peptide Synthesis - Lesson Summary
Hierarchical Structure of Proteins
-
Hierarchical Structure of Proteins - Learning Outcomes
-
Hierarchical Structure of Proteins: Secondary, Tertiary and Quaternary Structure
-
Ramachandran Plot and Protein Purification Techniques
-
Protein Purification Techniques
-
Introduction to Enzymes and its Kinetics
-
Enzyme Catalyzed Reactions and Introduction to the Catalytic Activity of Proteases
-
Hierarchical Structure of Proteins and Introduction to Enzymes and its Kinetics - Lesson Summary
Concept of Enzyme Inhibition and Synthetic Biology
-
Concept of Enzyme Inhibition and Synthetic Biology – Learning Outcomes
-
Enzymes Kinetics
-
Concept of Enzyme Inhibition
-
Irreversible Inhibition
-
Problems on Enzyme Kinetics and Enzyme Inhibition
-
Synthetic Biology
-
Production of Monoclonal Antibodies
-
Concept of Enzyme Inhibition and Synthetic Biology – Lesson Summary
Nucleic Acid and DNA Sequencing Method
-
Nucleic Acid and DNA Sequencing Method – Learning Outcomes
-
Catalytic Antibody
-
Nucleic Acid
-
DNA Double Helix
-
DNA Sequencing Method
-
Important Features of the DNA
-
Limitations of Sanger's Method of DNA Sequencing Method
-
Nucleic Acid and DNA Sequencing Method – Lesson Summary
Synthesis of Oligonucleotide and the Central Dogma
-
Synthesis of Oligonucleotide and the Central Dogma-Learning Outcomes
-
Synthesis of Oligonucleotide
-
Central Dogma: DNA Replication, Transcription and Translation
-
DNA Transcription
-
DNA Translation
-
Translation in Eukaryotes
-
DNA Ligase Mechanism
-
Synthesis of Oligonucleotide and the Central Dogma- Lesson Summary
Diploma in Organic Chemistry in Biology and Drug Development - First Assessment
Molecular Biology and Introduction to the Chemistry of Cofactors/Coenzymes
-
Molecular Biology and Introduction to the Chemistry of Cofactors/Coenzymes – Learning Outcomes.
-
Molecular Biology
-
Invitro Method of Amplifying a Piece of DNA by PCR
-
Chemistry of Cofactors/Coenzymes
-
Water Soluble Vitamins
-
Molecular Biology and Introduction to the Chemistry of Cofactors/Coenzymes – Lesson Summary
Chemistry of Cofactors/Coenzyme
-
Chemistry of Cofactors/Coenzyme – Learning Outcomes
-
Vitamin B1: Thiamine Pyrophosphate
-
Action of Metal Ion as a Cofactor
-
Coenzyme: Vitamin K
-
Vitamin B Complex Cofactors
-
Chemistry of Cofactors/Coenzyme – Lesson Summary
Introduction to the Drug Discovery Process and Neurotransmitters
-
Introduction to the Drug Discovery Process and Neurotransmitters – Learning Outcomes
-
Introduction to the Drug Discovery Process
-
Fundamental Principles of Drug Development Process
-
Combinatorial Chemistry
-
Neurotransmitters
-
Catechol Amine Based and GABA Neurotransmitters
-
Hypertension: Humoral Mechanism and Renin/Angiotensin System
-
Inhibitor Design of Angiotensin Converting Enzyme.
-
Introduction to the Drug Discovery Process and Neurotransmitters – Lesson Summary
Antimicrobial Drugs
-
Antimicrobial Drugs – Learning Outcomes
-
Antimicrobial Drugs
-
Chemistry of Penicillin
-
Resistance to Beta-lactam Antibiotics
-
Mechanistic Studies of Beta-lactamase
-
Non-beta Lactam Antibiotics
-
Mechanistic Enzymology of Isopenicillin N Synthase
-
Antimicrobial Drugs – Lesson Summary
Polyketide Biosynthesis and Introduction to Virus
-
Polyketide Biosynthesis and Introduction to Virus – Learning Outcomes
-
Polyketide Biosynthesis
-
Biosynthesis of Macrolide Polyketides and Introduction to Viruses
-
Anti-Viral Drugs
-
Polyketide Biosynthesis and Introduction to Virus – Lesson Summary
Anti-Viral Drugs, Cholesterol Biosynthesis and QSAR Principle
-
Anti-Viral Drugs, Cholesterol Biosynthesis and QSAR Principle – Learning Outcomes
-
Cancer and Chemotherapy
-
Anti-Cancer Drugs
-
Aromatase Inhibition and Anti-Ulcer Drugs
-
Cholesterol Lowering Agents
-
Cholesterol Biosynthesis
-
Pharmacokinetics and Pharmacodynamics
-
QSAR Principles
-
Anti-Viral Drugs, Cholesterol Biosynthesis and QSAR Principle – Lesson Summary
Diploma in Organic Chemistry in Biology and Drug Development - Second Assessment
Course assessment
Learning Outcomes
Having completed this course, you should be able to:
- Discuss the reasons why the field of biology and drug development process is important to an organic chemist
- Describe how the primary sequence of amino acids is determined
- List the important parameters for protein purification
- Define enzyme inhibitors and synthetic biology
- Discuss the distribution of nucleic acids in the eukaryotic cell and its structure
- Explain how DNA can be synthesized chemically
- Explain the mechanism of action of NAD⁺, NADP⁺ and cobalamin (vitamin B12)
- Explain the humoral mechanism for hypertension
- Match different antibiotics with their respective microorganism sources
- Discuss the mechanism of action of DNA virus, RNA virus, and retrovirus
- Explain why it is difficult to get a cure for cancer
- Discuss pharmacokinetics, pharmacodynamics, and how they are determined
Certification
All Alison courses are free to enrol, study and complete. To successfully complete this Diploma course and become an Alison Graduate, you need to achieve 80% or higher in each course assessment. Once you have completed this Diploma course, you have the option to acquire an official Diploma, which is a great way to share your achievement with the world. Your Alison Diploma is:
Ideal for sharing with potential employers - include it in your CV, professional social media profiles and job applications
An indication of your commitment to continuously learn, upskill and achieve high results
An incentive for you to continue empowering yourself through lifelong learning
Alison offers 3 types of Diplomas for completed Diploma courses:
Digital Diploma - a downloadable Diploma in PDF format, immediately available to you when you complete your purchase
Diploma - a physical version of your officially branded and security-marked Diploma, posted to you with FREE shipping
Framed Diploma - a physical version of your officially branded and security-marked Diploma in a stylish frame, posted to you with FREE shipping
All Diplomas are available to purchase through the Alison Shop. For more information on purchasing Alison Diplomas, please visit our FAQs. If you decide not to purchase your Alison Diploma, you can still demonstrate your achievement by sharing your Learner Record or Learner Achievement Verification, both of which are accessible from your Dashboard. For more details on our Diploma pricing, please visit our Pricing Page.
