Biology - DNA hybridisation
If single strands of DNA from different organisms are isolated and
combined, there is a tendency for the strands to bind according to the
base-pairing  rule (hybridisation).
The greater the hybridisation the harder it is to dissociate (separate)
the two strands. This would indicate a closer evolutionary relationship
between the species than if there was less hybridisation. A longer period
of time would have allowed differences in DNA to occur.
The genetic relationships between many species, including primates, have
been explored using this technique.
A molecular clock can be calibrated using dates established by dating
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