Loading
Notes
Study Reminders
Support
Text Version

Genetics of Axis Formation in Drosophila - Lesson Summary

Set your study reminders

We will email you at these times to remind you to study.
  • Monday

    -

    7am

    +

    Tuesday

    -

    7am

    +

    Wednesday

    -

    7am

    +

    Thursday

    -

    7am

    +

    Friday

    -

    7am

    +

    Saturday

    -

    7am

    +

    Sunday

    -

    7am

    +

The key points from this module are:

Syncytium means having a lot of nuclei in a common cytoplasm. One cell having multiple nuclei, so that is the situation in the Drosophila embryo.

The developmental potential of a nucleus depends on the region of the cytoplasm. Example Insects

Nurse cells are of GSC origin, which helps in nursing the developing oocyte.

One of the key components of this signalling from follicle cells to the oocyte is the localization of Par-1 protein.

Dorsal protein is required to make ventral, so in its absence, the embryo gets dorsalized.

The initial pattern established by Bicoid and Oskar's asymmetric localization in the oocyte is insufficient to make a complex organism.

The first asymmetry starts with the maternal factors that are products of the maternal germline.
The highest concentration of the Bicoid in the anterior activates the button head, empty spiracle, and orthodenticle. Caudal, which is a transcription factor in the posterior, activates the posterior gap genes knirps and giant.
The visible morphology is the segments, but internally, when you look at the embryo's molecular constellation, another segmented pattern exists, and that is the parasegments.

Humans are from Tetrapods, the four-legged animals.