Upon successful completion of this module, you will be able to:

• Explain how Thiele`s modulus affect the substrate profile

• Discuss Michaelis-Menten Kinetics in the enzyme system

• List the key points considered when designing the immobilized system for maximum efficiency

• Explain how the profile concentration change with other shapes in bioprocess

• Discuss the diffusion effects in immobilized cell systems

• Explain the common types of heat transfer application in bioreactor operation