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Module 1: Inheritance and Pathology

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Inheritance and Pathology - Lesson Summary

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The Key Contents from this Module are:

The sex of an individual is chromosomally based. Humans and other mammals have an X-Y system in which sex is determined by the presence or absence of the Y chromosome.

Mendelian Inheritance has its physical basis in the behaviour of chromosomes. It is the behaviour of chromosomes during meiosis that account for Mendel's laws of segregation and independent assortment.

Recombination is the exchange of nucleotide sequences between two homologous DNA molecules.

Alterations in the number of chromosomes or its structure can cause some genetic disorders.

Classical genetics experiments prove that DNA is the heritable factor that is transferred across generations.

Genetic diversity in prokaryotes can be promoted by means of:

Rapid reproduction
Mutation
Genetic recombination

Viruses consist of nucleic acid, surrounded by a protein coat and they replicate only in host cells.