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Bone, Vascular and Corneal Tissue Engineering – Lesson Summary

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Bone Anatomy
Bones support and protect the body and its organs. They also produce various blood cells, store minerals, and provide support for mobility in conjunction with muscle. Bone is made of bone tissue, a type of dense connective tissue.
There are two types of bone tissue: Cortical and Cancellous bone. Cortical bone is compact bone, while Cancellous bone is trabecular and spongy bone.

Bone Tissue Engineering
Bone Tissue Engineering (BTE) is based on the understanding of bone structure, bone mechanics, and tissue formation as it aims to induce new functional bone tissues. In other words, to successfully regenerate or repair bone, knowledge of the bone biology and its development is quite essential.

The following are the components of Bone Tissue Engineering:
Biomaterials
Cells

Growth Factors
Vascular Tissue Engineering
Vascular Tissue Engineering translates the knowledge of vascular biology to develop new therapeutic options for a wide range of clinical disorders. Blood vessels serve as conduits to deliver oxygen and nutrients to, and waste products away from, tissues.

Cornea
The cornea is the transparent part of the eye that covers the front portion of the eye. It covers the Pupil , Iris and the Anterior chamber. The cornea's main function is to refract, or bend, light.

The following are the Corneal Tissue Layers:
Corneal Epithelium
Bowman’s Layer
Central Stroma
Descemet’s Membrane
Corneal Endothelium

Corneal Tissue Engineering
Corneal Tissue Engineering emerges with the ambition of generating artificial corneas or other types of tissue-engineered products that lead to an optimal corneal regeneration, overcoming those major disadvantages of allogeneic corneal transplants.